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1

Cardionomics: a new integrative approach for screening cardiotoxicity of drug candidates

Gwathmey, Judith K, Tsaioun, Katya, Hajjar, Roger J

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2009

Langue:

english

Fichier:

PDF, 715 KB

english, 2009

2

Chronictreatment with Carvedilol improves ventricular function and reducesmyocyte apoptosis in an animal model of heart failure

Chukwuka C Okafor, Cynthia Perreault-Micale, Roger J Hajjar, Djamel Lebeche, Klara Skiroman, George Jabbour, Angelia A Doye, Michael X Lee, Nancy Laste, Judith K Gwathmey

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 863 KB

english, 2003

3

Calcium-sensitizing inotropic agents in the treatment of heart failure: A critical view

Roger J. Hajjar, Judith K. Gwathmey

Journal:

Cardiovascular Drugs and Therapy

Année:

1991

Langue:

english

Fichier:

PDF, 477 KB

english, 1991

4

Calcium handling in myocardium from amphibian, avian, and mammalian species: the search for two components

Judith K. Gwathmey, James P. Morgan

Journal:

Journal of Comparative Physiology B

Année:

1991

Langue:

english

Fichier:

PDF, 682 KB

english, 1991

5

Cellular mechanisms of paired electrical stimulation in ferret ventricular myocardium: relationship between myocardial force and stimulus interval change

Judith K. Gwathmey

Journal:

Journal of Comparative Physiology B

Année:

1992

Langue:

english

Fichier:

PDF, 674 KB

english, 1992

6

Sarcoplasmic reticulum calcium mobilization in right ventricular pressure-overload hypertrophy in the ferret: relationships to diastolic dysfunction and a negative treppe

Judith K. Gwathmey, James P. Morgan

Journal:

Pflügers Archiv European Journal of Physiology

Année:

1993

Langue:

english

Fichier:

PDF, 980 KB

english, 1993

7

Differential effects of reoxygenation on intracellular calcium and isometric tension

Roderick MacKinnon, Judith K. Gwathmey, James P. Morgan

Journal:

Pflügers Archiv European Journal of Physiology

Année:

1987

Langue:

english

Fichier:

PDF, 643 KB

english, 1987

8

Is contractility depressed in the failing human heart?

Judith K. Gwathmey, Ronglih Liao, Patrick A. Helm, Gowriharan Thaiyananthan, Roger J. Hajjar

Journal:

Cardiovascular Drugs and Therapy

Année:

1995

Langue:

english

Fichier:

PDF, 755 KB

english, 1995

9

SERCA2a in Heart Failure: Role and Therapeutic Prospects

Davide Gianni, Joachim Chan, Judith K. Gwathmey, Federica del Monte, Roger J. Hajjar

Journal:

Journal of Bioenergetics and Biomembranes

Année:

2005

Langue:

english

Fichier:

PDF, 79 KB

english, 2005

10

A Pilot Study of a New Chicken Model of Alcohol-Induced Cardiomyopathy

Nancy Morris, Catherine S. Kim, Angelia A. Doye, Roger J. Hajjar, Nancy Laste, Judith K. Gwathmey

Journal:

Alcoholism: Clinical and Experimental Research

Année:

1999

Langue:

english

Fichier:

PDF, 637 KB

english, 1999

11

Mentoring in a Post-Affirmative Action World

Jean E. Girves, Yolanda Zepeda, Judith K. Gwathmey

Journal:

Journal of Social Issues

Année:

2005

Langue:

english

Fichier:

PDF, 142 KB

english, 2005

12

Ventricular Arrhythmias after Left Ventricular Assist Device Implantation

MARWAN REFAAT, ELIE CHEMALY, DJAMEL LEBECHE, JUDITH K. GWATHMEY, ROGER J. HAJJAR

Journal:

Pacing and Clinical Electrophysiology

Année:

2008

Langue:

english

Fichier:

PDF, 109 KB

english, 2008

13

Rifalazil and Derivative Compounds Show Potent Efficacy in a Mouse Model of H. pylori Colonization

Rothstein, David M, Mullin, Steve, Sirokman, Klari, Söndergaard, Karen L, Johnson, Starrla, Gwathmey, Judith K, van Duzer, John, Murphy, Christopher K

Journal:

The Journal of Antibiotics

Année:

2008

Langue:

english

Fichier:

PDF, 289 KB

english, 2008

14

Effects of Pranidipine, a Calcium Channel Antagonist, in an Avian Model of Heart Failure

Catherine S. Kim, Charisse J. Ward, Akira Matsumori, Lee Goldberg, Angelia A. Doye, Quint McCoy, Judith K. Gwathmey

Journal:

Cardiovascular Drugs and Therapy

Année:

1999

Langue:

english

Fichier:

PDF, 262 KB

english, 1999

15

Calcium Channels in Cardiac Hypertrophy and Heart Failure

Stephen R. Shorofsky, C. William Balke, Judith K. Gwathmey

Journal:

Heart Failure Reviews

Année:

1998

Langue:

english

Fichier:

PDF, 317 KB

english, 1998

16

Heart Function Challenged with β-Receptor Agonism or Antagonism in a Heart Failure Model

Benny Washington, Karyn Butler, Angelia A. Doye, Monica Jang, Roger J. Hajjar, Judith K. Gwathmey

Journal:

Cardiovascular Drugs and Therapy

Année:

2001

Langue:

english

Fichier:

PDF, 119 KB

english, 2001

17

Mg-ATPase and CA2+activated myosin ATPase activity in ventricular myofibrils from non-failing and diseased human hearts – effects of calcium sensitizing agents MCI-154, DPI 201–106, and caffeine

Chukwuka Okafor, Ronglih Liao, Cynthia Perreault-Micale, Xiaoping Li, Toshiro Ito, Anna Stepanek, Angelia Doye, Pieter de Trombe, Judith K. Gwathmey

Journal:

Molecular and Cellular Biochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 124 KB

english, 2003

18

In vivo histamine release from brain cortex: the effects of modulating cellular and extracellular sodium and calcium channels

Benny Washington, James B Shaw, Jidong Li, Brian Fisher, Judith Gwathmey

Journal:

European Journal of Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 182 KB

english, 2000

19

Contribution of Abnormal Sarcoplasmic Reticulum ATPase Activity to Systolic and Diastolic Dysfunction in Human Heart Failure

Ulrich Schmidt, Roger J. Hajjar, Patrick A. Helm, Catherine S. Kim, Angelia A. Doye, Judith K. Gwathmey

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1998

Langue:

english

Fichier:

PDF, 183 KB

english, 1998

20

Protection of turkeys against furazolidone-induced cardiomyopathy

Judith K. Gwathmey, Robert L. Hamlin

Journal:

The American Journal of Cardiology

Année:

1983

Langue:

english

Fichier:

PDF, 768 KB

english, 1983

21

Inhibition of aftercontractions and phasic calcium release by yohimbine in ferret papillary muscle

G. Maurice Briggs, James P. Morgan, Judith K. Gwathmey

Journal:

European Journal of Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 287 KB

english, 1989

22

Post-extrasystolic potentiation and the force-frequency relationship: Differential augmentation of myocardial contractility in working myocardium from patients with end-stage heart failure

Preston J. Phillips, Judith K. Gwathmey, Marc D. Feldman, Frederick J. Schoen, William Grossman, James P. Morgan

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1990

Langue:

english

Fichier:

PDF, 1.02 MB

english, 1990

23

Modulation of calcium-activation in control and pressure-overload hypertrophied ferret hearts: Effect of DPI 201-106 on myofilament calcium responsiveness

Roger J. Hajjar, Judith K. Gwathmey

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 889 KB

english, 1991

24

Regulation of cardiac function in human heart failure

Roger J. Hajjar, Judith K. Gwathmey

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 94 KB

english, 1991

25

Effects of chronic alcohol on myocardial calcium homeostasis

Chad C. Olsen, James L. Ferguson, Marianne Piano, Judith K. Gwathmey, R.John Solaro

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1991

Langue:

english

Fichier:

PDF, 115 KB

english, 1991

26

Calcium-activated force in a turkey model of spontaneous dilated cardiomyopathy: Adaptive changes in thin myofilament Ca2+ regulation with resultant implications on contractile performance

Judith K. Gwathmey, Roger J. Hajjar

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1992

27

Cardiac gene therapy with SERCA2a: From bench to bedside

Judith K. Gwathmey, Alexan I. Yerevanian, Roger J. Hajjar

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2011

Langue:

english

Fichier:

PDF, 762 KB

english, 2011

28

Myofibrillar responsiveness to cAMP, PKA, and caffeine in an animal model of heart failure

Chukwuka C Okafor, Lori Saunders, Xiaoping Li, Toshiro Ito, Meredith Dixon, Anna Stepenek, Roger J Hajjar, June R Wood, Angelia A Doye, Judith K Gwathmey

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 197 KB

english, 2003

29

Morphological changes associated with furazolidone-induced cardiomyopathy: Effects of digoxin and propranolol

Judith K. Gwathmey

Journal:

Journal of Comparative Pathology

Année:

1991

Langue:

english

Fichier:

PDF, 2.19 MB

english, 1991

30

Preferential involvement of larger vessels in a rat model of diabetes-induced graft vasculopathy

Bernard Cantin, Dening Zhu, Peizhong Wen, Shyam N Panchal, Judith K Gwathmey, Gerald M Reaven, Hannah A Valantine

Journal:

The Journal of Heart and Lung Transplantation

Année:

2002

Langue:

english

Fichier:

PDF, 181 KB

english, 2002

31

Reversal of diabetes-induced rat graft transplant coronary artery disease by metformin

Bernard Cantin, Dening Zhu, Peizhong Wen, Shyam N. Panchal, Xiaohong Dai, Judith K. Gwathmey, Gerald M. Reaven, Hannah A. Valantine

Journal:

The Journal of Heart and Lung Transplantation

Année:

2002

Langue:

english

Fichier:

PDF, 163 KB

english, 2002

32

The effects of milrinone and piroximone on intracellular calcium handling in working myocardium from the ferret

Judith K. Gwathmey, James P. Morgan

Journal:

British Journal of Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 1.57 MB

english, 1985

33

Mechanisms of positive inotropic effects and delayed relaxation produced by DPI 201–106 in mammalian working myocardium: effects on intracellular calcium handling

Yasuki Kihara, Judith K. Gwathmey, William Grossman, James P. Morgan

Journal:

British Journal of Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 1.87 MB

english, 1989

34

Abnormal sarcoplasmic reticulum Ca2+ activity and uptake in human heart failure

Ulrich Schmidt, Maria Carles, Roger J. Hajjar, Thomas G. DiSalvo, Marc J. Semigran, G.William Dec, Jagat Narula, Ban-An Khaw, Judith K. Gwathmey

Journal:

Journal of the American College of Cardiology

Année:

1996

Langue:

english

Fichier:

PDF, 339 KB

english, 1996

35

Differential effects of cAMP and protein kinase A on sacroplasmic reticulum Ca2+ uptake in falling and nonfalling human myocardium

Ulrich Schmidt, Roger J. Hajjar, Robert H.G. Schwinger, Udo Bavendiek, Thomas G. DiSalvo, Marc J. Semigran, G.William Dec, Judith K. Gwathmey

Journal:

Journal of the American College of Cardiology

Année:

1996

Langue:

english

Fichier:

PDF, 151 KB

english, 1996

36

Inotropic and lusitropic effects of MCI-154 (6-[4-(4-pyridyl) aminophenyl]-4,5-dihydro-3(2H)-pyridazinone) on human myocardium

Sanford E. Warren, Yasuki Kihara, Janet Pesaturo, Judith K. Gwathmey, Preston Phillips, James P. Morgan

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1989

Langue:

english

Fichier:

PDF, 709 KB

english, 1989

37

An experimental model of acute and subacute viral myocarditis in the pig

Judith K. Gwathmey, Shoichiro Nakao, Patricia C. Come, Mary E.P. Goad, Juan R. Serur, Ann V. Als, Walter H. Abelmann

Journal:

Journal of the American College of Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 476 KB

english, 1992

38

The force—interval relationship in human myocardium

Ulrich Schmidt, Roger J. Hajjar, Judith K. Gwathmey

Journal:

Journal of Cardiac Failure

Année:

1995

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1995

39

Decreased inotropic but relatively preserved relaxation response to cyclic adenosine monophosphate-dependent agents in myopathic human myocardium

David E. Gutstein, Kristen Flemmal, Erika Bruce, Kerry E. Travers, Judith K. Gwathmey, Bernard J. Ransil, John E. Markis, William Grossman, James P. Morgan

Journal:

Journal of Cardiac Failure

Année:

1996

Langue:

english

Fichier:

PDF, 805 KB

english, 1996

40

Restoration of contractile function in isolated failing human ventricular cardiac myocytes by gene transfer of SERCA2a

Federica del Monte, Sian Harding, Judith K. Gwathmey, Anthony Rosenzweig, Roger J. Hajjar

Journal:

Journal of Cardiac Failure

Année:

1999

Langue:

english

Fichier:

PDF, 153 KB

english, 1999

41

Motility of thin filament regulated by troponin C from human myocardium with idiopathic dilated cardiomyopathy

Ronglih Liao, Judith K. Gwathmey, Chien-Kao Wang

Journal:

Journal of Cardiac Failure

Année:

1999

Langue:

english

Fichier:

PDF, 130 KB

english, 1999

42

Defects in calcium control

Federica Del Monte, Carrie M. Johnson, Anna C. Stepanek, Angelia A. Doye, Judith K. Gwathmey

Journal:

Journal of Cardiac Failure

Année:

2002

Langue:

english

Fichier:

PDF, 543 KB

english, 2002

43

Cerebrospinal fluid may mediate CNS ischemic injury

Yanming F Wang, Judith K Gwathmey, Guorong Zhang, Sulpicio G Soriano, Shunli He, Yanguang Wang

Journal:

Fluids and Barriers of the CNS

Année:

2005

Langue:

english

Fichier:

PDF, 4.52 MB

english, 2005

44

A Novel Mutant Cardiac Troponin C Disrupts Molecular Motions Critical for Calcium Binding Affinity and Cardiomyocyte Contractility

Lim, Chee Chew, Yang, Haijun, Yang, Mingfeng, Wang, Chien-Kao, Shi, Jianru, Berg, Eric A., Pimentel, David R., Gwathmey, Judith K., Hajjar, Roger J., Helmes, Michiel, Costello, Catherine E., Huo, Shua

Journal:

Biophysical Journal

Année:

2008

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2008

45

776-6 Myocardial Adenylyl Cyclase Activity in an Animal Model of Dilated Cardiomyopathy Treated Chronically with the Non-Selective β-blocker Carteolol

Khan, Farid, Hajjar, Roger J., Liao, Ronglih, Fuleihan, Farid, Bristow, Michael, Gwathmey, Judith K.

Journal:

Journal of the American College of Cardiology

Année:

1995

Langue:

english

Fichier:

PDF, 137 KB

english, 1995

46

1029-22 Effect of Cyclic GMP in Human Myocardium: Role of cAMP/cGMP Balance

Hajjar, Roger J., Gwathmey, Judith K.

Journal:

Journal of the American College of Cardiology

Année:

1995

Langue:

english

Fichier:

PDF, 158 KB

english, 1995

47

Modulation of Ventricular Function through Gene Transfer in vivo

Roger J. Hajjar, Ulrich Schmidt, Takashi Matsui, J. Luis Guerrero, Kyung-Han Lee, Judith K. Gwathmey, G. William Dec, Marc J. Semigran and Anthony Rosenzweig

Journal:

Proceedings of the National Academy of Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 1.68 MB

english, 1998

48

Targeting Sarcoplasmic Reticulum Calcium ATPase by Gene Therapy

Gwathmey, Judith K., Yerevanian, Armen, Hajjar, Roger J.

Journal:

Human Gene Therapy

Année:

2013

Langue:

english

Fichier:

PDF, 321 KB

english, 2013

49

Docosahexaenoic Acid Reduces the Incidence of Early Afterdepolarizations Caused by Oxidative Stress in Rabbit Ventricular Myocytes

Zhao, Zhenghang, Wen, Hairuo, Fefelova, Nadezhda, Allen, Charelle, Guillaume, Nancy, Xiao, Dandan, Huang, Chen, Zang, Weijin, Gwathmey, Judith K., Xie, Lai-Hua

Journal:

Frontiers in Physiology

Année:

2012

Langue:

english

Fichier:

PDF, 1.98 MB

english, 2012

50

Concomitant Intravenous Nitroglycerin With Intracoronary Delivery of AAV1.SERCA2a Enhances Gene Transfer in Porcine Hearts

Karakikes, Ioannis, Hadri, Lahouaria, Rapti, Kleopatra, Ladage, Dennis, Ishikawa, Kiyotake, Tilemann, Lisa, Yi, Geng-Hua, Morel, Charlotte, Gwathmey, Judith K, Zsebo, Krisztina, Weber, Thomas, Kawase,

Journal:

Molecular Therapy

Année:

2012

Langue:

english

Fichier:

PDF, 272 KB

english, 2012